Poster prize Magna Cum Laude for ZURT at Swiss Congress of Radiology

Idiopathic masticatory myalgia (IMM) is a common condition, with connection to the stiffening of masseter muscles. Botolinium Toxin type A (BTX-A, also known to the common public as “Botox”) injections are nowadays used as a treatment. However, both the BTX-A injection process and response monitoring are currently qualitative. The research work “Visualization of Intramuscular Botulinum Toxin Propagation without Contrast Media using a new B Flow Sequence” presents a new ultrasound method to quantitatively assess the distribution of BTX-A in the masseter and to reproducibly monitor stiffness variations in the muscle. This work is the result of a collaboration between ZURT and the Clinic of Masticatory Disorders of UZH. After proof of concept has been shown in porcine masseter, a clinical study is on-going with IMM patients. The goal is to assist dentists in planning BTX-A injection strategy and monitoring outcome.


First pulse-echo speed-of-sound (SoS) clinical study for breast tumor differentiation has been published in Investigative Radiology.

A significant SoS difference allowed differentiation between benign fibroadenoma (N=10) and malignant carcinoma (N= 10). This is an important step towards achieving non-invasive quantitative imaging biomarkers for breast cancer differentiation.

Ruby L, Sanabria SJ, Martini K, Desdes KJ, Vorburger D, Oezcan E, Frauenfelder T, Goksel O, Rominger MB. Breast Cancer Assessment With Pulse-Echo Speed of Sound Ultrasound From Intrinsic Tissue Reflections: Proof of Concept (2019). Investigative Radiology doi: 10.1097/RLI.0000000000000553


ZURT has been highlighted at the European Congress of Radiology ECR2019

ECR Today 03.03.2019: Musculoskeletal ultrasound elastography – can we pave the way towards standardisation? By Dr. med. Lisa Ruby

Nowadays, ultrasound elastography is an established method for evaluating the stiffness of the liver and tumours of the breast. In contrast to these application fields, numerous confounders have prevented the widespread use of this modality for musculoskeletal diseases in a standardised fashion. The Ultrasound Research and Translation group of the Institute of Diagnostic and Interventional Radiology in Zurich has been successful
in formulating steps towards better standardisation, broadening the application fields of musculoskeletal elastography. Link


A recently published research article about degenerative musculoskeletal disease (sarcopenia) at ZURT has been highlighted in an editorial of European Radiology 

Sconfienza LM (2019) Sarcopenia: ultrasound today, smartphones tomorrow? Eur Radio. 29 (1): 1-2. 
… In conclusion, sarcopenia represents a very important societal challenge. Aside from the new technologies, imaging specialists should be aware that they should play a pivotal role in this setting and the new data presented by Sanabria and colleagues certainly goes in this direction.

Sanabria SJ, Martini K, Freystätter G et al (2018) Speed of sound ultrasound: a pilot study on a novel technique to identify sarcopenia in seniors. Eur Radiol.